D-Cycloserine Enhancement of Exposure in Social Phobia
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test a drug called d-cycloserine to see if it can help people
with a condition called social phobia. Social phobia is also called "social anxiety
disorder." Social phobia is a constant fear of social or performance situations. Social
situations include group gatherings of any kind. Performance situations might include times
when a person would have to do something in public, such as speak up in class or at a
meeting. A person with this condition worries about being embarrassed, or about other
people's opinions. People with social phobia usually feel extremely anxious (nervous and
worried) about being the focus of attention. They often avoid social and performance
situations. This behavior can have a negative effect on the quality of their lives and
relationships.
In this study, we want to find out if d-cycloserine can help control social phobia when the
drug is added to the standard treatment for this condition. The standard treatment is
cognitive-behavior therapy (CBT). CBT is a form of talk therapy involving discussion with a
therapist, along with practicing the feelings or events that the person finds frightening.
Phase:
Phase 4
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborators:
Boston University National Institute of Mental Health (NIMH) National Institutes of Health (NIH) Southern Methodist University