D-Dimer Determined Anticoagulation INTENSITY in Patients With Mechanical Valve Replacement
Status:
Completed
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
The optimal intensity of oral anticoagulation in China patients undergoing mechanical valve
replacements is still controversial due to the different risk profiles of thrombophilia and
bleeding in Chinese patients. Elevated D-dimer could reflect a pro-thrombogenic or
prothrombotic state, and thus might be used to decide the intensity of oral anticoagulation.
This study was to evaluate whether elevated D-dimer levels could help to determine the
intensity of oral anticoagulation in patients with mechanical heart valve prostheses.