Overview

D-cycloserine (DCS) Pretreatment + CBT + Nicotine Replacement Therapy for Smoking Cessation (DCS)

Status:
Terminated

Trial end date:
2017-08-01

Target enrollment:

Participant gender:

Summary

1. Compare the relative efficacy of ten weeks of once weekly 250 mg D-cycloserine (DCS) vs. placebo (both in conjunction with cognitive behavioral therapy (CBT) and nicotine replacement therapy (NRT) on reducing cigarette smoking in treatment-seeking nicotine-dependent outpatients. 2. Compare the relative efficacy of ten weeks of once weekly 250 mg DCS vs. placebo on the process of extinction and the memory encoding process.

Phase:

Phase 1/Phase 2

Details

Lead Sponsor:

Mclean Hospital

Collaborator:

American Lung Association

Treatments:

Cycloserine
Nicotine