Overview

DAPAgliflozin Versus Thiazide Diuretic in Patients With Heart Failure and Diuretic RESISTance

Status:
Recruiting
Trial end date:
2022-10-30
Target enrollment:
Participant gender:
Summary
To assess the effect of dapagliflozin compared with metolazone, added to furosemide, on diuresis and decongestion in hospitalised heart failure patients with diuretic resistance, and renal impairment. The primary analysis will be in patients with HFrEF but patients with HFpEF will also be recruited in an ancillary study and included in supplementary analyses.
Phase:
Phase 3
Details
Lead Sponsor:
NHS Greater Glasgow and Clyde
Collaborator:
University of Glasgow
Treatments:
2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol
Dapagliflozin
Metolazone