Overview

DAW2020 on OSA Endotypic Traits

Status:
Recruiting
Trial end date:
2022-07-15
Target enrollment:
Participant gender:
Summary
Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. Some OSA patients with low arousal threshold wake up prematurely during an obstructive event and do not have time for spontaneous upper airway (UA) dilator muscle recruitment. As a consequence they are exposed to apnea and hypopnea cycling. In this protocol the investigators will test the effect of DAW2020 administered before sleep on OSA phenotype traits and OSA severity during sleep.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Brigham and Women's Hospital