DMPA & High Dose Oral Progestin (MPA) Tablets in Outpatient Treatment of Acute Excessive Vaginal Bleeding

• Status: Completed
• Trial end date: 2012-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to investigate the effectiveness and acceptability of high dose MPA (20mg oral 3 times a day) for 3 days combined with an injection of DMPA 150 mg intramuscularly in the treatment of acute heavy, prolonged uterine bleeding who have been identified as being eligible for outpatient management

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Women's Health Care Clinic, Torrance, California
• Treatments: Medroxyprogesterone; Medroxyprogesterone Acetate

Criteria

Inclusion Criteria:

• Age 18- 50

• Non-pregnant

• Candidate for outpatient management

• Able to understand and follow instructions

• Vital signs stable

• No severe anemia

• No medical conditions requiring transfusion

Exclusion Criteria:

• Pregnancy

• Breast cancer current or in last 5 years

• Allergy to MPA or DMPA

• Previous hormonal therapies

• Unstable vital signs

• Bleeding excessive enough to require surgical therapy or hospital admission

• Desire for pregnancy in next 6 months