Overview
DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide.
Status:
Completed
Completed
Trial end date:
2016-12-01
2016-12-01
Target enrollment:
0
0
Participant gender:
Female
Female
Summary
BACKGROUND: Malar melasma has a chronic and recurrent character that may be related with epigenetic changes.Phase:
Early Phase 1Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Universidad Autonoma de San Luis PotosÃTreatments:
Niacin
Niacinamide
Nicotinic Acids
Sunscreening Agents
Tretinoin
Criteria
Inclusion Criteria:Clinical diagnosis of malar melasma by a specialist. No previous treatment at the beginning
of the study.
Exclusion Criteria:
Use of medications associated with the development of melasma. Pregnant or lactating
patients. Presence of concomitant diseases associated with the development of melasma. or
other facial hyperpigmentations (thyroid, liver).
Have received treatment in the last 2 months. Regular use of sunscreen.