Daily Nevirapine to Prevent Mother to Infant Transmission of HIV
Status:
Completed
Trial end date:
2007-09-01
Target enrollment:
Participant gender:
Summary
Infants who are breast-fed by HIV infected mothers have an increased risk of becoming
infected with HIV. Standard therapy for the prevention of HIV infections in infants included
zidovudine (ZDV) prior to the onset of labor, a single dose of nevirapine (NVP) for women
during labor, and a single dose of NVP for newborns given 72 hours after birth. This study
will determine if giving low dose daily NVP to breastfed infants of HIV infected mothers, in
addition to standard therapy, will be more effective than standard therapy alone at
preventing HIV infections in these infants.
Phase:
Phase 3
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)