Overview

Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections

Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Because of its prolonged terminal half-life, dalbavancin is an extremely attractive option in treating Gram-positive infections caused by S. aureus including MRSA, and streptococcal species. Systemic bacterial infections due to Staphylococci such as osteomyelitis and septic arthritis, are conditions which require prolonged IV therapy, typically for at least 3-6 weeks, though sometimes more. Due to dalbavancin's prolonged terminal half-life, it may offer the opportunity to substantially reduce costs and morbidity in native joint and prosthetic joint infections with one infusion every fourteen days until completion of therapy.
Phase:
Phase 4
Details
Lead Sponsor:
Infectious Diseases Physicians, Inc.
Collaborator:
Johns Hopkins University
Treatments:
Cefazolin
Dalbavancin
Daptomycin
Nafcillin
Teicoplanin
Vancomycin