Overview

Death to Onchocerciasis and Lymphatic Filariasis (DOLF) Triple Drug Therapy for Lymphatic Filariasis

Status:
Completed
Trial end date:
2018-05-31
Target enrollment:
Participant gender:
Summary
The DOLF Triple Drug Therapy for Lymphatic Filariasis study will determine the frequency, type and severity of adverse events following triple-drug therapy (IVM+DEC+ALB, IDA) compared to the standard two-drug treatment (DEC+ALB, DA) in infected and uninfected individuals in a community in 5 different countries. The objective is to acquire safety, efficacy, and acceptability data to assess the safety and acceptability of the IDA drug combination.
Phase:
N/A
Details
Lead Sponsor:
Washington University School of Medicine
Collaborators:
Case Western Reserve University
Indian Council of Medical Research
Treatments:
Albendazole
Diethylcarbamazine
Ivermectin