Decitabine With or Without Bortezomib in Treating Older Patients With Acute Myeloid Leukemia
Status:
Active, not recruiting
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
This randomized phase II trial studies how well giving decitabine with or without bortezomib
works in treating older patients with acute myeloid leukemia. Drugs used in chemotherapy,
such as decitabine, work in different ways to stop the growth of cancer cells, either by
killing the cells,by stopping them from dividing, or by stopping them from spreading.
Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for
cell growth. It is not yet known whether decitabine works better when given with or without
bortezomib in treating acute myeloid leukemia.