Overview

Decitabine and Selinexor in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Status:
Completed
Trial end date:
2016-11-26
Target enrollment:
Participant gender:
Summary
This phase I trial studies the side effects and best dose of Selinexor when given together with decitabine in treating patients with acute myeloid leukemia that has returned after treatment (relapsed) or does not respond to treatment (refractory). Drugs used in chemotherapy, such as decitabine and Selinexor, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
Phase:
Phase 1
Details
Lead Sponsor:
Bhavana Bhatnagar
Collaborators:
Karyopharm Therapeutics Inc
Karyopharm Therapeutics, Inc
Treatments:
Azacitidine
Decitabine