Overview

Decreasing the Incidence of Delirium After Cardiac Surgery

Status:
Withdrawn

Trial end date:
2017-08-01

Target enrollment:
0

Participant gender:
All

Summary

In critically ill surgical patients, delirium (confusion and disorientation) is extremely common and is associated with longer hospital length of stay, mortality, cost, and long term cognitive impairment. The goal of the study is to establish whether benzodiazepines (a sedative, anti-anxiety drug) should be used as part of standard of care or be eliminated by comparing the chances of delirium in cardiac surgery patients between two groups: a group that receives benzodiazepines during surgery versus a group that does not receive benzodiazepines during surgery. Benzodiazepines have historically been used in cardiac anesthesia to decrease the risk of anesthesia awareness. The current standard of care is to keep the patient on inhaled anesthesia throughout the surgery which eliminates the need for intraoperative use of benzodiazepines. Benzodiazepines are still used based on practitioner preference. Findings of this study will allow all anesthesiologists to make more informed decisions about what level of care our patients need.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

University of California, Los Angeles

Treatments:

Fentanyl
Midazolam
Propofol

Criteria

Inclusion Criteria:

- Adult patients' undergoing coronary artery bypass grafting or single valve procedures.

Exclusion Criteria:

- Patients who have baseline cognitive dysfunction,

- Patients with hearing problems,

- Patients currently on benzodiazepines