Deep Neuromuscular Block and Sugammadex Versus Standard of Care on Quality of Recovery in Patient Undergo Elective Laparoscopic Cholecystectomy

• Status: Unknown status
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Single center, prospective, randomized, single blinded, parallel group and controlled, assessor-blinded trial to compare the impact of Deep neuromuscular block and Sugammadex versus Standard of care on Quality of recovery in patient undergo elective laparoscopic cholecystectomy using PQRS at different time-point: 15 minutes (T15), 40 minutes (T40), one(D1) and three(D3) days after surgery

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ho Chi Minh City University of Medicine and Pharmacy; University of Medicine and Pharmacy at Ho Chi Minh City
• Collaborator: Merck Sharp & Dohme Corp.
• Treatments: Atropine; Rocuronium

Criteria

Inclusion Criteria:

• All adult patients (> 18 years) scheduled for elective Laparoscopic Cholecystectomy with American Society of Anesthesiologist (ASA) class I-III in Hospital of University of Medicine and Pharmacy-Ho Chi Minh City

Exclusion Criteria:

• Patients with ASA class IV

• Age <18 years

• Inability to inform consent

• History or suspected with neuromuscular disorders

• Allergies to rocuronium or sugammadex, anesthetics or narcotics drugs

• A history of malignant hyperthermia

• A contraindication with neostigmine administration

• Pregnancy or breastfeeding

• Renal and liver insufficiency are excluded from this study