Deep Neuromuscular Block on Postoperative Delirium in Lumbar Surgery

• Status: Enrolling by invitation
• Trial end date: 2024-02-28
• Target enrollment: 0
• Participant gender: All

Summary

The effect of deep neuromuscular blockade (NMB) during spine surgery reduced postoperative pain and bleeding in recent studies. Therefore by reducing these two factors, which were the contributing factors for postoperative delirium, deep NMB is expected to reduce the postoperative delirium. This study was designed to determine whether the deep NMB lowered the incidence of delirium after lumbar surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Korea University Guro Hospital
• Treatments: Rocuronium

Criteria

Inclusion Criteria:

• Aged 70 and more;

• Scheduled for an elective lumbar spine surgery;

• ASA physical status 1-3

Exclusion Criteria:

• Diagnosed neuromuscular disorder;

• Contraindications to the study drug, e. g. known allergy or hypersensitivity, hypotension, bradycardia, higher grade atrioventricular block;

• Patient with pre-existing cognitive impairment or dementia