Deep Phenotyping of Cutaneous T Cell Lymphoma, Type Mycosis Fungoides
Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Mycosis fungoides (MF) is an ultra-orphan disease of which the etiology remains unknown. MF
is diagnosed by correlating clinical appearance with histopathological analysis of often
multiple invasive skin punch biopsies. To move patient care and the development of novel
treatments for MF forward, objective, sensitive and reliable tools that are preferably
non-invasive are desired. Therefore, the objective of the current study is to phenotype the
early stages of mycosis fungoides in detail and to assess the response of chlormethine (CL)
gel monotherapy. With this approach the investigators aim to detect novel biomarkers and to
establish methodologies for the (non-)invasive monitoring of MF.