Delineating Swallowing Impairment and Decline in ALS

• Status: Recruiting
• Trial end date: 2023-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to 1) evaluate the discriminant ability of simple clinical markers to detect swallowing impairment in individuals with ALS, 2) develop and validate a minimally invasive clinical screening tool for use at multidisciplinary ALS clinics, and 3) determine the natural history of swallowing impairment and decline in ALS.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Florida
• Collaborators: National Institute of Neurological Disorders and Stroke (NINDS); National Institutes of Health (NIH)
• Treatments: Capsaicin

Criteria

Inclusion Criteria:

• diagnosis of probable or definite ALS

Exclusion Criteria:

• allergies to barium or capsaicin

• History of stroke

• Head and Neck Cancer

• Other disorder that might contribute to swallowing impairment

• Not enrolled in other research investigations that might impact swallowing

• Not pregnant