Overview

Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant

Status:
Recruiting
Trial end date:
2026-09-01
Target enrollment:
Participant gender:
Summary
This is a Phase 2 randomized, double-blinded, placebo-controlled study that will evaluate multiple potential pharmacotherapeutic interventions for PTSD utilizing an adaptive platform trial design. Intervention C - Daridorexant will assess the safety and efficacy of daridorexant in participants with PTSD. Please see NCT05422612 for information on the S-21-02 Master Protocol.
Phase:
Phase 2
Details
Lead Sponsor:
U.S. Army Medical Research and Development Command
Collaborators:
Berry Consultants
Cambridge Cognition Ltd
Citeline
Idorsia Pharmaceuticals Ltd.
PPD