Desflurane,Brain Natriuretic Peptide and Cardiac Surgery
Status:
Completed
Trial end date:
2014-09-30
Target enrollment:
Participant gender:
Summary
During coronary artery bypass grafting (CABG) operations with cardiopulmonary bypass (CPB),
the use of desflurane continuously or intermittently may have effects on serum brain
natriuretic peptide (BNP) levels. The aim is to investigate the association between
desflurane, serum BNP values, and clinical outcomes during CABG operations. In a prospective,
randomized, double-blinded study, desflurane inhalational anesthesia was administered either
continuously or intermittently (Group 1; n=60 versus Group 2; n=62). The preoperative and
postoperative BNP levels at 24, 48 and 72 hours after surgery were collected. Outcomes were
recorded.
Phase:
N/A
Details
Lead Sponsor:
Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital