Detection of Consciousness by EEG and Auditory Evoked Potentials

• Status: Completed
• Trial end date: 2003-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of the present investigation is to analyze EEG and auditory evoked potentials at the transition from consciousness to unconsciousness and vice versa. A set of electroencephalographic and auditory evoked potential parameters should be identified that allows separation of consciousness from unconsciousness (reflected by responsiveness/unresponsiveness to command). The study is based on data of 80 patients undergoing general anesthesia with remifentanil and either sevoflurane or propofol.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Technische Universität München
• Treatments: Anesthetics; Propofol; Remifentanil; Sevoflurane

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) physical status 1-2

• Adult patients

Exclusion Criteria:

• Patients with contraindications to the study drugs

• psychiatric or neurologic disease

• drug abuse or medication known to affect the central nervous system

• pregnancy

• indication for rapid sequence induction