Detection of Coronary Stenosis With Intravenous Microbubbles

• Status: Withdrawn
• Trial end date: 2014-03-01
• Target enrollment: 0
• Participant gender: All

Summary

To detect coronary artery disease by both coronary and carotid artery imaging and myocardial perfusion imaging using a new low mechanical index real time system.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Nebraska

Criteria

Inclusion Criteria:

• subjects scheduled for routine echocardiogram to look for evidence of Coronary artery disease or a stress echocardiogram

• women of child-bearing potential must be taking a medically approved form of birth control with a negative urine pregnancy test

• be conscious and coherent, and be able to communicate effectively with study personnel

• last eight patients will be diabetics who smoke

• provide informed consent after receiving a verbal and written explanation of the purpose and nature of the study

Exclusion Criteria:

• severe valvular heart disease by Doppler Echocardiography

• females of child-bearing potential who are not taking a medically approved method of birth control will be excluded. If the patient is pregnant she will be excluded.

• patients who are allergic to blood or blood products will be excluded

• have contraindication to Optison, Definity, or PESDA (pulmonary HTN, cardiac shunt)

• non diabetics, non smokers