Determination of Adipocyte Parameters in Iliac Crest Biopsies From Post Menopausal Women
Status:
Completed
Trial end date:
1989-04-01
Target enrollment:
0
Participant gender:
Female
Summary
To evaluate the effect of estrogen treatment on adipocytic and osteoblastic parameters by
histomorphometrically measuring adipocyte volume (AV/TV) and adipocyte numbers in goldner's
stained iliac crest bone biopsy specimens collected from subjects recruited in the study (IRB
number 21B85). The adipocytic parameters will be then correlated with osteoblastic parameters
obtained previously during the course of the initai study involving the effect of transdermal
estrogen on bone turnover in postmenopausal osteoporotic women.