Overview

Determine the ED50 of Dexmedetomidine to Facilitate LMA Insertion During Anaesthesia Induction

Status:
Unknown status

Trial end date:
2015-04-01

Target enrollment:
0

Participant gender:
Female

Summary

Dexmedetomidine can be used as a co-induction agent to facilitate laryngeal mask airway (LMA) insertion with minimal effect on respiratory function. The purpose of the study was to determine the median effective dose (ED50) of dexmedetomidine to facilitate LMA insertion during anaesthesia induction with propofol 2.0 mg/kg.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Guangzhou General Hospital of Guangzhou Military Command

Treatments:

Anesthetics
Dexmedetomidine
Propofol

Criteria

Inclusion Criteria:

1. ASA Ⅰ ~ Ⅱ women undergoing Laparoscopic surgery.

2. Written informed consent from the patient or the relatives of the participating
patient.

3. BMI:18.5～25

Exclusion Criteria:

1. Mental illness can not match

2. epidural anesthesia contraindicated

3. People who have Slow-type arrhythmias

4. Chronic renal failure

5. Alcohol or drug abuse

6. Already taking gabapentin, pregabalin, benzodiazepin or antidepression drug