Determining the Necessity for Postoperative Antibiotics After Salivary Stent Placement
Status:
Recruiting
Trial end date:
2021-08-01
Target enrollment:
Participant gender:
Summary
Salivary duct stent placement is a common practice to maintain duct patency after salivary
duct repair or interventional sialoendoscopy; procedures performed to manage salivary duct
pathology such as stenosis, traumatic injury or most commonly salivary duct stones. It is
common practice for patients to receive perioperative antibiotics while undergoing
interventional sialoendoscopy and postoperative oral antibiotic therapy with Clindamycin or
Augmentin for 10-14 days, if a short term (2 week) salivary duct stenting was considered
necessary due to the nature of the intervention. However, In reviewing the literature, there
are controversial trials that indicate post-operative antibiotics may not be best practice in
all surgical scenarios, as the adverse events ie. gastrointestinal disturbances, nausea,
Clostridium difficile (C.diff) infection and antibiotic resistance over time surrounding
overuse of antibiotics may outweigh the clinical need for the antibiotic regiment and the
chances of post-operative infection.
Phase:
Phase 4
Details
Lead Sponsor:
Our Lady of the Lake Hospital
Collaborator:
Louisiana State University Health Sciences Center in New Orleans