Determining the Sensitivity of Sentinel Lymph Nodes Identified With Robotic Fluorescence Imaging
Status:
Completed
Trial end date:
2017-01-01
Target enrollment:
Participant gender:
Summary
Description:
This is a multi-institutional study investigating the sensitivity and negative predictive
value of sentinel lymph nodes mapped with robotic assisted near infrared imaging after
cervical injection of indocyanine green (ICG) dye for women with stage I endometrial or
cervical cancer at the time of their robotic surgical staging.
Patients will receive cervical injection of 1mg ICG after induction of anesthesia followed by
sentinel lymph node mapping using robotic assisted fluorescence imaging. The sentinel lymph
nodes identified will be removed and sent for ultraprocessing by pathology. The non-sentinel
pelvic and para-aortic (if indicated) non-sentinel nodes will be removed and sent for routine
pathologic processing according to standard of care for these surgical procedures. The
pathologic results of the sentinel and non-sentinel nodes will be evaluated for sensitivity
and negative predictive value in their ability to detect metastatic disease.