Development and Evaluation of a Methadone Protocol for Severe Chronic Pain Management
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
Methadone is a synthetic mu opioid agonist that has been proved as clinically effective in
pain management. However, methadone usage for pain control in Thailand has been limited
because physicians are not familiar with its dosing and concern about the risk of drug
accumulation and cardiac arrhythmia. Therefore, this prospective study was conducted to
evaluate the efficacy and safety of a methadone protocol in Thai patients with severe chronic
noncancer and cancer pain.