Dex on Microcirculation in SS-A Double-blinded Study

• Status: Unknown status
• Trial end date: 2017-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators preliminary study showed that dexmedetomidine might improve microcirculation in septic shock patients. To test this effect, the investigators will conduct double-blinded study.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Southeast University, China
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• Septic shock patients despite early goal directed therapy

• Agree to participate this study

Exclusion Criteria:

• Age< 18

• Pregnancy

• Bradycardia (HR<55bpm)

• Systolic Blood Pressure < 80 mmHg / Mean arterial pressure < 50 mmHg on maximal support

• Death imminent

• Unlikely to survive 90 days

• Acute liver failure

• Dementia

• High-grade block in the absence of a functioning pacemaker.