Dexamethasone Versus Dexmedetomidine as Adjuvants for Nerve Blocks
Status:
Completed
Trial end date:
2019-04-30
Target enrollment:
Participant gender:
Summary
When used as perineural (PN) adjuvants to local anesthetics (LAs), dexamethasone (DX) and
dexmedetomidine (DXD) have been well documented to prolong the duration of peripheral nerve
blocks. These drugs have important differences in terms of cost and safety profiles. This
randomized controlled trial (RCT) will compare PN DX and PN DXD for ultrasound-guided
infraclavicular brachial plexus blocks (ICBs).
Since analgesic and sensory duration can be influenced by factors different to block, motor
block duration is the main outcome. The protocol is designed as an equivalency trial and
hypothesize that both drugs result in similar durations. The equivalency margin is set at 3
hrs.
Phase:
N/A
Details
Lead Sponsor:
University of Chile
Treatments:
Anesthetics Anesthetics, Local BB 1101 Dexamethasone Dexamethasone acetate Dexmedetomidine