Dexamethasone Versus Local Infiltration Technique for Tonsillectomy in Children

• Status: Completed
• Trial end date: 2015-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Tonsillectomy is one of the most frequent surgical operations performed in children [1-4]. It is usually associated with postoperative nausea and vomiting (PONV) with an incidence ranging from 23% to 73% [2]. Dexamethasone has been shown to be effective in reducing PONV after tonsillectomy using standardized anesthetic technique [2, 5-7]. Previous studies utilizing a different technique, the pre-incision infiltration of local anesthesia, had shown to decrease post-tonsillectomy pain, reduce analgesic consumption and provide a rapid return to normal activity [8, 9]. Given the effectiveness of dexamethasone and the pre-incision infiltration anesthetic technique, it would be beneficial to compare the effect of each on PONV.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Makassed General Hospital
• Treatments: Acetaminophen; Anesthetics; Anesthetics, Local; BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Propacetamol; Tramadol

Criteria

Inclusion Criteria:

Patients scheduled for total or partial tonsillectomy with or without adenoidectomy

Exclusion Criteria:

Patients who received antiemetics, steroids, antihistaminics, or psychoactive drugs within 24 hours before surgery.

Patients who are suspected to have malignant neoplasm and signs of acute pharyngeal infection..

Patients who have asthma, diabetes mellitus, bleeding problems, and allergy towards bupivacaine.