Dexamethasone and Ketamine on Change of Postoperative Mood

• Status: Completed
• Trial end date: 2017-06-12
• Target enrollment: 0
• Participant gender: Female

Summary

Ketamine and dexamethasone have been known to be effective postoperative pain. Many studies also have reported these two drugs might change mood such as depression. This study aimed to investigate the effect of each drug individually with their combination on perioperative change of mood in patients undergoing gynecologic surgery

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Wonkwang University Hospital
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Ketamine

Criteria

A total of 93 patients

Inclusion Criteria:

• patients who were scheduled for laparoscopic gynecologic surgery

Exclusion Criteria:

• Patients with hepatic and renal insufficiency, history of allergy to the study drugs, previous gastric ulcer, diabetes mellitus, and receiving analgesic, antiemetic, antihistamine, steroids or psychiatric drugs within 24 hours before surgery steroids