Dexamethasone and Ondansetron Versus Placebo for Postoperative Nausea and Vomiting

• Status: Completed
• Trial end date: 2015-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators want to test if it is indicated to associate dexamethasone and ondansetron in obese patients having bariatric surgery under total intra-venous closed-loop anesthesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hopital Foch
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Ondansetron

Criteria

Inclusion Criteria:

• Adult patients aged 18-75 years

• Scheduled for bariatric surgery under total intra-venous closed-loop anesthesia

• Apfel score equal or greater than 2

• Consenting to participate in the study

Exclusion Criteria:

• Pregnant, breast feeding women

• Allergy

• Contraindication to dexamethasone

• Contraindication to ondansetron

• Contraindication to propofol, remifentanil, morphine, ketoprofen

• Limit to the use of bispectral index