Dexamethasone and Respiratory Function After Mastectomy

• Status: Unknown status
• Trial end date: 2016-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

Preoperative dexamethasone reduces symptoms after different surgical procedures including mastectomy in breast cancer, but the effect in the postoperative respiratory function remains unknown. The aim of this protocol was to determine if the administration of a single dose of dexamethasone during the preoperative, could improve respiratory function and postoperative symptoms of patients undergoing mastectomy in breast cancer.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Instituto Mexicano del Seguro Social
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate

Criteria

Inclusion Criteria:

• confirmed diagnosis of breast carcinoma

Exclusion Criteria:

• patients with a classification of the American Society of Anesthesiologists classes III and IV.

• pregnancy

• during menstruation

• during steroid therapy

• severe diabetes mellitus (serum HbA1c> 8%)

• opioids, sedatives or painkillers less than a week before the mastectomy

• history of alcohol or drugs

• patients with a history of inner ear disease and / or severe PONV after any surgical procedure performed in the past