Dexamethasone at Night vs at Induction on PONV After Laparoscopic Cholecystectomy
Status:
Completed
Trial end date:
2023-11-20
Target enrollment:
Participant gender:
Summary
Since the peak effect of the dexamethasone is delayed to 12-16 hours after iv administration,
we designed this study to investigate the effect of administering dexamethasone at-night
before surgery versus at-induction (the standard timing) in prevention of postoperative
nausea and vomiting after laparoscopic cholecystectomy.
A pilot randomized controlled study (60 cases) will be started to explore the potential
difference, ensure correct and rigorous data collection, and calculate the sample size for a
larger pragmatic trial.