Overview

Dexamethasone in the Treatment of Bronchiolitis in Patients With Either Eczema and or Family History of Asthma

Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
The investigators hypothesized that oral Dexamethasone in addition to nebulized Salbutamol will improve the Bronchiolitis Clinical Severity Score,duration of treatment in the short stay unit,need for hospitalization and readmissions to the pediatric emergency in a subgroup of patients diagnosed as Bronchiolitis with either eczema and or a parental or sibling history of Asthma. Two groups randomized will be given Nebulized Ventolin plus either oral Dexamethasone or placebo for 5 days. Bronchiolitis severity score plus vital signs will be recorded regularly until patient is fit for discharge. Patients will be discharged on Ventolin inhaler and to complete the five days course of oral Dexamethasone Patients will be followed up for 7 days post discharge by telephone.
Phase:
Phase 1
Details
Lead Sponsor:
Hamad Medical Corporation
Treatments:
Albuterol
BB 1101
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate