Dexketoprofen and Etoricoxib in Patients Undergoing Hip Arthroplasty
Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
The main purpose of this study was to determine the plasma and central nervious system
pharmacokinetics of dexketoprofen and etoricoxib. The secondary aim was to asses their effect
on the concentrations of interleukin 6, prostaglandin E2 and other proinflammatory markers
both in plasma and cerebrospinal fluid. Thirdly, the investigators aimed to evaluate their
efficacy in postoperative pain treatment.