Dexmedetomidine Adjuvant to General Anesthesia of Abdominal Hysterectomy

• Status: Unknown status
• Trial end date: 2020-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

To assess the effect of perioperative Dexmedetomidine infusion on Interleukin 6 and cortisol level in patients undergoing general anesthesia for total abdominal hysterectomy

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Suez Canal University
• Treatments: Anesthetics; Dexmedetomidine; Sympatholytics

Criteria

Inclusion Criteria:

• American Society of Anesthesiology physical status Grade I = (normal healthy patients)

• American Society of Anesthesiology physical status Grade II = (patients with mild systemic disease and no functional limitations)

• Patients scheduled for abdominal hysterectomy.

Exclusion Criteria:

• Pre-operative regular medication with opioids and benzodiazepines, alcohol abuse, known sleep disturbance, known endocrine disease.

• Known allergy to Dexmedetomidine.

• Heart block greater than first degree.

• Medication known to affect the sympathetic response or hormonal secretion.

• Smokers