Dexmedetomidine Compared to Ketofol for Sedation in Paediatrics

• Status: Recruiting
• Trial end date: 2021-12-30
• Target enrollment: 0
• Participant gender: All

Summary

Dental fear and anxiety remain common problems that should be managed by both the dentist and the anesthetist. The currently available evidence for safe and effective sedative drugs for children undergoing the dental procedure is scarce The aim of this study was to compare the safety and efficacy of intravenous ketofol versus dexmedetomidine (Dex) as premedications a sedative in anxious children undergoing dental pulp therapy

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ain Shams University
• Treatments: Dexmedetomidine; Ketamine; Propofol

Criteria

Inclusion Criteria:

• ASA-I children,

• aged 5-10 years-old,

• requiring dental pulp therapy

Exclusion Criteria:

• ASA class ≥ II;

• previous experience with GA or Conscious sedation (CS);

• dental treatment expected to exceed 45 minutes;

• history of allergy to local anesthetics, Dex, propofol, ketamine, eggs, or soya;

• respiratory tract infections