Dexmedetomidine Infusion on Intraoperative Propofol,Fentanyl Requirements in Spine Surgery for Pediatric Cancer Patients

• Status: Recruiting
• Trial end date: 2023-10-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this trial is to investigate whether the effect of a low-dose dexmedetomidine infusion will decrease propofol consumption or not through a double blinded randomized controlled trial done in children cancer hospital 57357.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Cancer Hospital Egypt 57357
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• spinal cord tumor resection based on magnetic resonance imaging (MRI) studies.

• age between 5 -18 years old

• American Society of Anesthesiologists (ASA) physical status II or III.

Exclusion Criteria:

• Emergency spine surgery

• Cardiac patients

• Any individual with stage 4 or greater chronic kidney disease (eGFR< 30 ml/min) and/or requiring dialysis

• liver failure defined as a history of cirrhosis or fulminant hepatic failure

• Preoperative dexmethatodine use

• Preoperative systolic hypertension defined by a systolic blood pressure greater than 130 mmHg in the surgical admission suite

• Enrolled in another study within 30 days.