Dexmedetomidine-Ketamine Infusion in Breast Surgeries

• Status: Completed
• Trial end date: 2020-08-14
• Target enrollment: 0
• Participant gender: Female

Summary

• This is a prospective randomized double blind controlled study.

• Female patients undergoing radical mastectomy will be included in this stydy where they will be randomly allocated into;- Control group in which patients will receive continuous infusion of normal saline.

Dexmedetomidine-Ketamine group which patients will receive continuous infusion of ketamine and dexmedetomidine.

The intraoperative and postoperative opioid consumption will be measured. Also, the postoperative pain score and the incidence of chronic pain will be assessed.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tanta University
• Collaborator: Mohamed Elsayed Afandy
• Treatments: Dexmedetomidine; Ketamine

Criteria

Inclusion Criteria:

• Female patients aged 50-70 years, ASA class I-II, and presented for elective radical mastectomy.

Exclusion Criteria:

• Patients refused to participate.

• Patients with known or suspected or known allergy to the used medication.

• Patients with preoperative chronic pain,

• Patients received preoperative opioids or gabapentoids.

• Patients with major cardiac, renal, respiratory, or hepatic disease.

• Uncooperative patients.

• Obese patients with BMI >36