Dexmedetomidine Reduces Emergence Delirium in Children Undergoing Tonsillectomy With Propofol Anesthesia

• Status: Completed
• Trial end date: 2017-07-30
• Target enrollment: 0
• Participant gender: All

Summary

Dexmedetomidine (DEX) is safe and effective in reducing ED following sevoflurane anesthesia. The investigators intend to study the efficacy of DEX in reducing ED in children undergoing tonsillectomy with and without adenoidectomy using total intravenous anesthesia (TIVA) with propofol .

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
• Treatments: Anesthetics; Dexmedetomidine; Fentanyl; Nalbuphine; Propofol; Remifentanil; Rocuronium

Criteria

Inclusion Criteria:

• Children

• ASA I or II

• tonsillectomy with or without adenoidectomy

Exclusion Criteria:

• Allergy to dexmedetomidine

• Allergy to anesthetic drugs

• History of neurological disease

• History of neuromuscular disease

• History of renal disease

• History of hepatic disease

• craniofacial anomalies

• History of cardiac disease

• History of respiratory disease