Intravenous sedation is used frequently for the relief of pain and anxiety associated with
oral surgical procedures performed under local anesthesia. The purpose of this study is to
learn about patient and surgeon satisfaction with sedation using Dexmedetomidine in
combination with midazolam alone or with midazolam plus low dose ketamine while having wisdom
teeth removed.
The sedation produced by dexmedetomidine is unique in that it mimics natural sleep, a unique
quality not shared by other drugs. Dexmedetomidine is often used in anesthesia in hospital
operating rooms and has been approved by the US Food and Drug Administration for the use
planned in this study.