Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium
Status:
Recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
Delirium is a frequently occurred cerebral complication in elderly patients after surgery,
and its occurrence is associated with worse outcomes. Sleep disturbances is considered to be
one of the most important risk factors of postoperative delirium. Previous studies showed
that, for elderly patients admitted to the ICU after surgery, low-dose dexmedetomidine
infusion improved the quality of sleep and decreased the incidence of delirium. The
investigators hypothesize that, for elderly patients after cancer surgery, dexmedetomidine
supplemented analgesia can also decrease the incidence of delirium, possibly by improving
sleep quality. The purpose of this multicenter, randomized controlled trial is to investigate
the impact of dexmedetomidine supplemented analgesia on the incidence of delirium in elderly
patients after cancer surgery.
Phase:
N/A
Details
Lead Sponsor:
Peking University First Hospital
Collaborators:
Affiliated Hospital of Hebei University Beijing Chao Yang Hospital Beijing Ditan Hospital Beijing Shijitan Hospital, Capital Medical University Beijing Tsinghua Chang Gung Hospital Guizhou Provincial People's Hospital Peking University International Hospital Qingdao Municipal Hospital Shanxi Provincial Cancer Hospital The Second Affiliated Hospital of Air Force Medical University The Third Xiangya Hospital of Central South University Tianjin Hospital of ITCWM-Nankai Hospital Zhongda Hospital Southeast University