Overview

Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery

Status:
Recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
A majority of the elderly patients undergo surgery for malignant tumors. For these patients, postoperative tumor recurrence and metastasis are main factors that worsen long-term outcomes. The investigators hypothesize that dexmedetomidine supplemented analgesia in elderly patients after cancer surgery may help to maintain immune function and improve long-term outcomes, possibly by relieving stress and inflammatory response, improving analgesic efficacy and sleep quality, and reducing delirium incidence.
Phase:
N/A
Details
Lead Sponsor:
Peking University First Hospital
Collaborators:
Affiliated Hospital of Hebei University
Beijing Chao Yang Hospital
Beijing Ditan Hospital
Beijing Shijitan Hospital, Capital Medical University
Beijing Tsinghua Chang Gung Hospital
Guizhou Provincial People's Hospital
Peking University International Hospital
Qingdao Municipal Hospital
Shanxi Provincial Cancer Hospital
The Second Affiliated Hospital of Air Force Medical University
The Third Xiangya Hospital of Central South University
Tianjin Hospital of ITCWM-Nankai Hospital
Zhongda Hospital Southeast University
Treatments:
Analgesics
Dexmedetomidine
Morphine