Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine for Intermediate Cervical Plexus Block
Status:
Recruiting
Trial end date:
2023-04-15
Target enrollment:
Participant gender:
Summary
Background: Many thyroidectomy patients suffer from postoperative pain that could delay early
hospital discharge and place a significant burden on both the patient and the healthcare
team. Bilateral intermediate cervical plexus block (ICPB) provides good analgesia for neck
surgery, including thyroidectomy. However, the duration of a single-shot nerve block is
usually short. Therefore, adjuvants are used in peripheral nerve blocks.
Objectives: To compare the safety and efficacy of dexmedetomidine versus dexamethasone as
adjuvants to bupivacaine in ultrasound-guided intermediate cervical plexus block in patients
undergoing total thyroidectomy under general anesthesia.
Patients and Methods: This is a randomized, double-blind, phase four, prospective clinical
trial; carried out on 60 patients, who were candidates for total thyroidectomy under general
anesthesia at our hospital. Patients were randomly allocated into two equal groups; group A,
received bilateral ICPB with isobaric bupivacaine plus dexmedetomidine, and group B, received
bilateral ICPB with isobaric bupivacaine plus dexamethasone.