Dexmedetomidine Versus Fentanyl on Postoperative Analgesic Profile in Laparoscopic Sleeve Gastrectomy

• Status: Completed
• Trial end date: 2023-05-20
• Target enrollment: 0
• Participant gender: All

Summary

Dexmedetomidine (Dex) activates the α2 adrenergic receptor that is present within the locus coeruleus, leading to anxiolysis, hypnosis, analgesia, and sedation.

We conducted our research to compare the effects of fentanyl and DEX on the postoperative analgesic profile and complications in morbidly obese patients after sleeve gastrectomy.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Helwan University
• Treatments: Dexmedetomidine; Fentanyl

Criteria

Inclusion Criteria:

• body mass index (BMI) of 35 kg/m2 or more.

• American Society of Anesthesiology (ASA) physical status of II-III.

• all participants would have a laparoscopic sleeve gastrectomy (LSG).

Exclusion Criteria:

• allergy to α2 -adrenergic agonist.

• kidney, liver, neuromuscular disorders, and cardiac disease.

• or patients on opioid medications.