Dexmedetomidine Versus Gabapentin Premedication on the Emergence Agitation After Rhinoplasty

• Status: Recruiting
• Trial end date: 2023-04-30
• Target enrollment: 0
• Participant gender: All

Summary

To compare the effect of intramuscular dexmedetomidine versus oral gabapentin premedication on the emergence agitation after rhinoplasty.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ain Shams University
• Treatments: Dexmedetomidine; Gabapentin

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists grade I or II.

• Sex: Both sexes.

• Age between 18 and 40 years.

• Patients scheduled for rhinoplasty under general anesthesia

Exclusion Criteria:

• Declining to give written informed consent.

• History of allergy to the medications used in the study.

• history of cardiovascular diseases including bradycardia, heart block, and hypertension.

• History of chest problems including bronchial asthma.

• Had a history of drug or alcohol abuse.

• Taking opioids or sedative medications.

• Inability to communicate with patients to evaluate postoperative pain.

• Hepatic or renal failure.

• Psychiatric disorders with antipsychotics or antidepressants.

• Bleeding disorders, antiplatelets (aspirin, clopidogrel), or anticoagulant (warfarin).