Dexmedetomidine Versus Propofol in Conjunction With Regional Block for Shoulder Arthroscopy
Status:
Completed
Trial end date:
2018-09-15
Target enrollment:
Participant gender:
Summary
Operative shoulder arthroscopy under regional block anesthesia often presents with
hemodynamic challenges for the anesthesiologist, knowing that a low systolic blood pressure
is required to minimize the bleeding. Regional anesthesia is successfully performed to many
patients in whom tracheal intubation or the placement of a laryngeal tube is undesired.
Propofol has traditionally been used to provide sedation in patients undergoing shoulder
arthroscopy under regional anesthesia. In contrast to Propofol, Dexmedetomidine is a highly
selective α-2 adrenoceptor agonist that has been shown to provide sedation, analgesia and
anxiolytic effects with minimal respiratory depression. Due to the effect of both drugs on
blood pressure, the investigators set out to compare intraoperative hemodynamics of both
drugs, along with the surgeon's satisfaction and the degree of comfort provided to patients
undergoing interscalene brachial plexus block for shoulder arthroscopy. The investigators
also assessed whether the type of anesthetic agent used for sedation accounted for other
differences in intra and post-operative outcome measures.