Dexmedetomidine Versus Propofol in Vitreoretinal Surgery

• Status: Completed
• Trial end date: 2013-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators would like to determine if using Dexmedetomidine alone or in a reduced dose can prevent or reduce the incidence of adverse effects, while providing adequate sedation, and respiratory stability as compared to propofol.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rutgers, The State University of New Jersey
• Treatments: Dexmedetomidine; Propofol

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists rating of I-III

• good renal and liver function

Exclusion Criteria:

• renal and hepatic insufficiency

• uncontrolled diabetes

• uncontrolled hypertension

• severe cardiac disease Class III or IV

• heart blocks

• chronic use of sedatives, narcotics, alcohol or illicit drugs

• allergy to either propofol or dexmedetomidine

• pregnancy or inability to tolerate technique of the study drugs