Dexmedetomidine and Ketamine in MRI

• Status: Completed
• Trial end date: 2018-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this research study is to examine the effects of two commonly used anesthetic drugs, dexmedetomidine and ketamine, have on the shape and muscle tone of the upper airway in children, adolescents, and young adults.

The results of this study will help in making the best decisions regarding the anesthesia medications used for sedation outside of the operating room.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Hospital Medical Center, Cincinnati
• Treatments: Anesthetics; Dexmedetomidine; Ketamine

Criteria

Inclusion Criteria:

• Patient requires anesthesia for a MRI scan of the brain or MRI brain/spine

• Patient must be 1 to 18 years of age

• Patients legally authorized representative has given written informed consent to participate in the study

Exclusion Criteria:

• Allergy to dexmedetomidine or ketamine

• History or obstructive sleep apnea

• The patient has a life-threatening medical condition (ASA status 4, 5, or 6)

• The patient is not scheduled to receive anesthesia sedation for the MRI

• Patient has a history or a family history of malignant hyperthermia