Dexmedetomidine and Propofol in Mechanically Ventilated Patients by Using Salivary Alpha-amylase as a Stress Marker

• Status: Completed
• Trial end date: 2024-04-11
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to compare the efficacy of dexmedetomidine and propofol on decreasing stress in mechanically ventilated patients by using salivary alpha-amylase as a stress marker.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tanta University
• Treatments: Dexmedetomidine; Propofol

Criteria

Inclusion Criteria:

• Age 18 to 65 years old.

• Both sexes.

• Newly mechanically ventilated.

Exclusion Criteria:

• Patients who used inhaled steroids.

• Patients who used any medication that could affect salivary glands (such as antihypertensive, antidepressants or antipsychotic drugs).

• Those with smoking and drinking habits.

• Patients on adrenoreceptor agonist or antagonist therapy.

• Pregnant female.

• Known hypersensitivity to the study drugs.

• Women using oral contraceptive or were in their menstrual cycle.